SLU-PP-332 vs Retatrutide vs Tesamorelin: Three Different Answers to Metabolic Decline
By: Dr. Max MacCloud, DO, ND, PhD Quick answer: SLU-PP-332 vs retatrutide vs tesamorelin is a comparison of three different tools. Retatrutide is a peptide with substantial human weight-loss data. Tesamorelin is a peptide approved to reduce visceral fat in a specific population. SLU-PP-332 is a small-molecule exercise mimetic studied only in mice. They address […]
MOTS-c and Retatrutide Together: The Mitochondrial Case for Sequencing Before You Stack
By: Dr. Max MacCloud, DO, ND, PhD Quick answer: No published human trial has tested MOTS-c and retatrutide together. The rationale is mechanistic: retatrutide reduces food intake while raising energy demand, and MOTS-c affected muscle metabolism in animal studies. MOTS-c and retatrutide are not FDA-approved. Protein and resistance training, not any peptide, are what protect […]
The GLP-1 Hunger Games: Semaglutide vs Tirzepatide vs Retatrutide — A Cynic’s Guide to Picking Your Metabolic Potion
By: Dr. Max MacCloud [DO, ND, PhD] There comes a moment in every health optimization expert’s life when you realize the pharmaceutical industry has finally built something more addictive than Instagram. In reality, they found something “natural” and modified it to make it more effective and patentable. I’m talking, of course, about the GLP-1 arms […]
I Read Every Retatrutide Trial So You Don’t Have To. (Also, the Scale Is Lying to You.)
By: Dr. Max MacCloud [DO, ND, PhD] Let me save you some time on retatrutide. If you’ve opened Instagram or LinkedIn in the last six months, you’ve seen the same carousel seventeen times: a pastel-colored infographic explaining that retatrutide is a “triple hormone receptor agonist” with a cute little diagram of three overlapping circles, like […]
Tirzepatide Sarasota: The Dual-Action Weight Loss Peptide That’s Outperforming Semaglutide
By: Dr. Max MacCloud [DO, ND, PhD] If you’ve been told weight loss is just “eat less and move more,” congratulations. You’ve been handed one of modern medicine’s favorite bedtime stories. It sounds tidy. It sounds scientific. It also falls apart the second you apply it to actual human physiology instead of a fifth-grade chalkboard […]
Semaglutide vs. Tirzepatide for Weight Loss in Sarasota: Which Is Right for You, the GLP-1, the G-2, or the Latest G3?
By: Dr. Max MacCloud [DO, ND, PhD] Let’s be honest for a second: Western medicine is essentially a glorified repair shop for a car being driven by a driver that has no clue how to operate and care for properly. We spend billions “managing” diseases that we created with bad advice, sketchy food choices, scores […]